Short communication: Towards saliva-based screening for sleeping sickness?

Short communication: Towards saliva-based screening for sleeping sickness?

A pilot study was carried out on the detection of trypanosome-specific antibodies in saliva for diagnosis of sleeping sickness. All twenty-three saliva samples of parasitologically confirmed Trypanosoma brucei gambiense patients tested positive in an indirect enzyme-linked immunosorbent assay, whereas all 14 saliva samples of a negative control group remained negative. Trypanosome-specific anti...

Sleeping Sickness Wakes Again

Sleeping sickness of horses was, as reeentiy as the IQSO's, the most devastating livestock disease in the United States. Horses died by the hundreds of thousands in the Midwestern United States, in California, and along the Atlantic seaboard at a period which coincided with the beginning of the sharp decline in the use of horses on the farm. Losses were so severe in some areas that the inevitab...

Sleeping sickness surveillance: an essential step towards elimination.

In the last decades, with little or no surveillance sleeping sickness has returned to alarming levels comparable to the early twentieth century. Sixty million people are considered at risk but only 3-4 million are under surveillance, yielding some 45 000 new cases annually. It is estimated that at least 300 000-500 000 people are presently infected. Despite the almost universal presence of the ...

Sleeping sickness – human African trypanosomiasis

Rapid diagnostic test for sleeping sickness.

n engl j med 368;11 nejm.org march 14, 2013 1069 thereby reduce the duration of mechanical ventilation. Many, but not all, of these strategies were mentioned in our article. We also agree with the suggestion to avoid benzodiazepines, as has been recommended in the recent Clinical Practice Guidelines for the Management of Pain, Agitation, and Delirium in Adult Patients in the Intensive Care Unit...